The Seattle Seahawks will face an injury-riddled St. Louis Rams team when the teams square off in a Week 4 matchup at the Edward Jones Dome in St. Louis on Sunday.

Wednesday's Rams practice saw five players sit out with injuries, the most notable of whom was running back Steven Jackson. The veteran back sat out to rest the groin injury that held him out of practice all of last week. Jackson did manage to play in Week 3 despite the injury, picking up 29 yards on 11 carries against the Bears.

Defensive tackle Matt Conrath (knee), safety Matt McDaniels (hamstring), defensive end Eugene Sims (illness), and offensive tackle Rodger Saffold (knee) also sat out Wednesday's practice.

The Rams have had depth issues at left tackle during the young 2012 season. Saffold missed Sunday's game and Wayne Hunter, who replaced him, was limited in practice on Wednesday because of a sore knee.

Defensive tackle Michael Brockers (ankle) was also a limited participant in Wednesday's practice.

Kickoff is scheduled for 10 a.m. PT and the game will be televised on FOX.